Week 10 preview: Seahawks at Raiders, prediction, odds and injury report

By Kyle Alm. Published 2026-11-09, updated 2026-11-09.

Our pick: Seattle 23, Las Vegas 17. Why. Not advice.

Seattle is 5-4 after beating Arizona 17-3 on Sunday at Lumen Field, without seven injured players and with Drew Lock at quarterback. Las Vegas is 4-5 after a 38-17 loss at San Francisco in which it turned the ball over five times in the second half, per the club. The Raiders are in their first season under Klint Kubiak, who was Seattle’s offensive coordinator for its 2025 championship season, per the Raiders, with Kirk Cousins at quarterback. Kickoff is Sunday, November 15, at 1:05 p.m. Pacific on CBS at Allegiant Stadium, and Seattle’s bye follows. This is the first look, written the morning after both games; we update it with the injury reports, the quarterback decision and the line through the week.

The injury picture

The first practice reports are due Wednesday, November 11, so neither team has a report yet. The day-by-day table will be on the injury report.

Seattle’s quarterback. Sam Darnold missed the Arizona game with a quadricep injury, and Lock, who started in his place on an elbow that had limited him in practice for three weeks, hurt his oblique in the second half. He went to the injury tent after an incomplete third-down pass and came back the next time Seattle had the ball, per the club. Mike Macdonald, asked after the game whether he knew Darnold’s status, said: “I don’t. I think we’ll probably re-evaluate early in the week. I’m assuming we’re going to probably have to make a decision on who we’re going to get ready and how we’re going to do that. Drew’s situation, we’ll have to evaluate that as well. Unfortunately, it seems like it’s kind of up in the air right now.” Lock: “I was able to finish with it, but we’ll get it looked at and go from there, but not too bad.” Asked if he was confident he could play, he said, “Yeah. Yeah.” Jalen Milroe was the backup on Sunday, and Adrian Martinez is on the practice squad.

Seattle. Seven players were inactive against Arizona with injuries, per the club: Darnold (quadricep, ribs), left tackle Charles Cross (ankle), left guard Quenton Nelson (knee), defensive tackle Leonard Williams (stinger), outside linebacker Uchenna Nwosu (ankle), receiver Rashid Shaheed (knee) and nose tackle Brandon Pili (back). Nelson is week-to-week after what Macdonald called a minor knee procedure, per the club. The club’s postgame posts reported no other new injuries from Sunday. Who is back for Las Vegas is not known until Wednesday’s report.

Las Vegas. The Raiders’ recap of the 49ers game mentions no injuries, and the club has not posted an update since; their first report is also Wednesday. We add it when it posts.

What the Raiders have done

Las Vegas started 3-0, beating Miami 27-13 at home and winning 26-14 at the Chargers and 35-27 at New Orleans, then lost four straight: 30-27 to Kansas City, 45-17 at New England, 33-30 to Buffalo and 35-21 to the Rams, all but New England at home. It won 38-33 at the Jets on November 1, then lost 38-17 at San Francisco, per ESPN’s results. It has scored 238 points and allowed 268, 29.8 a game, and it has allowed at least 30 in six straight games, per the club.

At San Francisco, the Raiders trailed 14-0 after two 49ers drives and 21-10 at halftime. Cousins bobbled the first snap of the second half and threw an interception that Jaden Dugger returned 35 yards for a touchdown, Brock Bowers and Michael Mayer each lost a fumble, Mayer’s at the 1-yard line, and Cousins threw two more interceptions, per the club. He finished 22 of 32 for 216 yards with a touchdown and the three interceptions, his first three-interception game since Week 13 of 2024, per the club. Las Vegas ran for 24 yards, San Francisco for 190, and the 49ers held the ball for 38:18, per ESPN’s game data. Kubiak: “The game has to be balanced. You can be a running and throwing team [and] when you’re throwing it every time, that’s not easy.”

Bowers caught seven passes for 111 yards and a touchdown, a week after seven for 92 and two touchdowns at the Jets. Rookie safety Treydan Stukes had his second interception, and per the club the defense has 14 takeaways.

The matchups that decide it

Seattle’s quarterback, and his protection. Whoever starts, Seattle did not allow a sack on Sunday, a week after Darnold was sacked three times by Chicago, with Josh Jones at left tackle and Grey Zabel and Anthony Bradford at guard. Lock has not turned the ball over in three appearances this season, per the club. If neither Darnold nor Lock can go, Milroe would start.

Seattle’s run game against a defense that just gave up 190 yards. Zach Charbonnet ran 16 times for 77 yards on Sunday and Jadarian Price added 24 yards and a team-high 54 receiving. San Francisco ran at will up the middle on Las Vegas, per the club, and Las Vegas has allowed 30 points or more in six straight.

Seattle’s defense against Bowers. Arizona gained 74 yards from scrimmage on its first drive and 124 on the rest, and its All-Pro tight end, Trey McBride, caught seven passes for 54 yards with Nick Emmanwori on him much of the day, per the club. Bowers is the same kind of test. Seattle’s defense has allowed 18 points a game, 162 in nine.

Turnovers. Seattle did not turn the ball over against Arizona; Las Vegas turned it over five times at San Francisco.

The line

As of Monday morning, November 9, at 6:39 a.m. Pacific, DraftKings has Seattle by 3.5, total 43.5, moneyline Seattle -185 and Las Vegas +154, per ESPN’s game data. VegasInsider’s consensus at the same time was Seattle -3.5 and 43.5, with Seattle -170; FanDuel and Hard Rock had Seattle -3. It opened at Seattle by 7, with Seattle -340 on the moneyline, per VegasInsider. ESPN’s matchup predictor gives Seattle a 68.5 percent chance. The quarterback news this week will move it. At 3.5, our 23-17 pick below would be a Seattle cover by two and a half points. The Seahawks odds page has Seattle’s record against the number: 3-4-2 against the spread through nine games, with five of nine under the total.

Washington allows sports betting only in person at tribal casinos, and there is no legal online sportsbook in the state. Nevada’s rules are different, so check the law where you are. We carry no sportsbook advertising, and the numbers are here because fans ask, not as advice.

Prediction

Seattle 23, Las Vegas 17. Seattle’s defense has held six of nine opponents to 23 points or fewer and just allowed 198 yards to Arizona; Las Vegas has allowed at least 30 points six games running and gave the ball away five times on Sunday. The case for the Raiders is Seattle’s quarterback: if neither Darnold nor Lock is healthy, Seattle’s offense goes in with its third option, and Kubiak ran Seattle’s offense last season. If Seattle runs the ball as it did against Arizona and does not turn it over, it covers; if Cousins and Bowers find the middle of the field the way Chicago did, Las Vegas stays inside the number. We lean under 43.5: Seattle’s games are five under and four over, and its last two under totals came with the defense allowing 3 points. Not advice. We revisit the pick when Seattle names its quarterback and after Friday’s game status reports.

The game guide has the CBS details and what we know about getting to Allegiant Stadium. Our Week 9 recap has how Seattle beat Arizona.

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